Scientists Develop Gel That Can Regrow Tooth Enamel

Scientists Develop Gel That Can Regrow Tooth Enamel
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Researchers at the University of Nottingham have created a new protein-based gel capable of rebuilding and repairing tooth enamel, potentially transforming dental care.

As reported by SciTechDaily, the innovative material, described in Nature Communications, mimics the body’s natural enamel-forming process. When applied to teeth, it creates a thin, durable coating that penetrates the surface and fills microscopic cracks. Acting as a structural framework, the gel draws calcium and phosphate ions from saliva, encouraging the growth of new minerals through a process known as epitaxial mineralization.

Unlike fluoride treatments, the gel contains no fluoride and can regenerate enamel-like tissue, restoring both strength and structure. The research team, led by Professor Álvaro Mata and Dr. Abshar Hasan, found the regenerated enamel performed like natural enamel under real-life conditions such as chewing and brushing.

The technology, already being developed by the university’s start-up Mintech-Bio, could be available as a clinical treatment within a year, offering new hope for millions affected by tooth decay and enamel erosion.