Turtles could hold secret to cancer prevention in humans

Turtles could hold secret to cancer prevention in humans
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A new study led by Dr. Ylenia Chiari at the University of Nottingham reveals that cancer is extremely rare in turtles, affecting only about 1% of individuals—much lower than mammals (10%) and birds (3%), Earth.com reported. By analyzing decades of zoo health records across Europe and the U.S., researchers found that turtles rarely develop cancer, and when they do, it seldom spreads or targets specific organs.

Turtles’ strong cancer resistance is linked to their slow metabolism, robust antioxidant defenses, and unique genetic mutations that enhance tumor suppression and maintain DNA stability. Species like the Galapagos and Aldabra giant tortoises, despite their large size and long lifespans, show remarkably low cancer rates, defying typical biological expectations.

The study highlights turtles as promising models for understanding cancer resistance and healthy aging. Researchers emphasize the importance of zoos in providing long-term data and supporting conservation. While most data come from captive turtles, further studies using turtle cell lines could uncover how their cells resist cancer triggers.

Conservation remains critical, as many turtle species face threats from habitat loss, illegal trade, and climate change. Protecting turtles not only preserves biodiversity but may also safeguard genetic secrets with potential medical benefits for humans. The study is published in BioScience.