Study Finds Allergic Rhinitis May Lower Lung Cancer Risk

Study Finds Allergic Rhinitis May Lower Lung Cancer Risk
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A recent meta-analysis published by researchers in Scientific Reports highlights a potential link between allergic conditions and reduced lung cancer risk. The study reviewed data from 10 case-control and cohort studies involving over 3.8 million participants, assessing the relationship between allergic rhinitis (AR), eczema, and lung cancer.

The findings suggest that individuals with AR had 26% lower odds of developing lung cancer (OR 0.74), while eczema showed no statistically significant association overall. However, subgroup analysis revealed a possible protective effect of eczema among males. In general, allergic diseases were linked to a lower risk of lung cancer, particularly in men and populations from the Americas.

Researchers hypothesize that allergies may enhance immune surveillance through IgE-mediated responses, potentially helping detect and eliminate malignant cells. Conversely, chronic immune stimulation could also promote cancer risk, highlighting a complex relationship.

While results indicate an inverse association between allergies and lung cancer, the study acknowledges limitations, including reliance on self-reported data and limited geographic representation. Asthma was excluded from the analysis due to its known association with increased lung cancer risk. The authors call for further research to clarify the biological mechanisms and improve prevention strategies based on allergic profiles.