Scientists Discover Potential Diabetes Treatment in Venom of Deadly Cone Snail

Researchers at the University of Utah have identified a promising diabetes treatment derived from the venom of the geography cone snail, SciTech Daily reported yesterday.

A study in Nature Communications reveals that consomatin, a toxin mimicking the hormone somatostatin, could lead to more effective medications for diabetes and hormone disorders.

Led by Dr. Helena Safavi, the team found that consomatin specifically targets proteins in human cells, unlike somatostatin, which interacts with multiple proteins. This selectivity may reduce side effects associated with current treatments.

The cone snail uses consomatin to immobilize its prey by regulating blood sugar levels, showcasing the potential of natural venoms in drug discovery. Additionally, researchers have identified another toxin resembling insulin, suggesting multiple glucose-regulating compounds in the venom.

Dr. Ho Yan Yeung, the study’s first author, highlighted the evolutionary advantage of these toxins, emphasizing their potential for innovative therapies in human medicine.