Scientists Report Major Progress Toward a Universal Cancer Vaccine
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\nResearchers at the University of Massachusetts Amherst have demonstrated that a newly developed nanoparticle-based vaccine can prevent several aggressive cancers in mice, showing strong potential for a future universal cancer vaccine. <\/p>\n
According to SciTechDaily, the experimental formulation protected against melanoma, pancreatic cancer and triple-negative breast cancer, with tumor-free survival rates reaching up to 88 percent depending on cancer type.<\/p>\n
The vaccine uses a lipid nanoparticle \u201csuper adjuvant\u201d engineered to activate multiple immune pathways while delivering cancer-specific antigens. In melanoma tests, 80 percent of vaccinated mice remained tumor-free for the duration of a 250-day study, while all unvaccinated mice developed tumors and died within 35 days. The vaccine also stopped melanoma from metastasizing to the lungs.<\/p>\n
A second set of experiments using tumor-cell lysate showed similarly strong results across multiple cancers. Vaccinated mice not only rejected initial tumor challenges but also resisted later systemic exposure to cancer cells.<\/p>\n
Researchers say the vaccine\u2019s effectiveness stems from powerful T-cell activation and long-lasting \u201cmemory immunity.\u201d The team has launched a startup, NanoVax Therapeutics, to explore clinical development of the platform for both cancer prevention and treatment.<\/p>\n","protected":false},"excerpt":{"rendered":"
Scientists Report Major Progress Toward a Universal Cancer Vaccine ——————— Researchers at the University of Massachusetts Amherst have demonstrated that a newly developed nanoparticle-based vaccine can prevent several aggressive cancers in mice, showing strong potential for a future universal cancer vaccine. According to SciTechDaily, the experimental formulation protected against melanoma, pancreatic cancer and triple-negative breast …<\/p>\n","protected":false},"author":1,"featured_media":137681,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":{"facebook_108372464460192_245495985553329":""},"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[8955],"tags":[],"class_list":["post-137682","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-news"],"yoast_head":"\n