Millions of Syrian children could be living in a state of "toxic stress" due to prolonged exposure to the horrors of war, aid group Save the Children says.
The damage to an entire generation of children could soon become irreversible without immediate help, it adds.
The stress of war has led to increased bedwetting, self-harm, suicide attempts and aggressive behavior among many children, according to a new report.
The findings are based on hundreds of interviews in Syria.
Save the Children says its study is the largest of its kind into the mental health and well-being of Syria's children amid the war, which began in 2011 and has left more than 300,000 people dead.